On the side of the main sanctuary are two shrines: the Lady Chapel on the west and the Chapel of St. Joseph on the east. They represent some of the most valuable and high quality elements in the Cathedral and have a notably Spanish Gothic character. The Lady Chapel has three carved scenes representing the flight into Egypt, the Holy Family, and the finding of the Child Jesus in the Temple. The statues are of St. Lawrence (right top); St. Bernard (right center); St Bonaventure (right bottom); St. Bartholomew (left top); the Cure of Ars (left center); and St. Blaise (left bottom).
The St. Joseph Chapel on the west side has three carved nativity scenes depicting the annunciation to the Shepherds, the birth of Christ and the Adoration of the Magi. The carved figures are those of St. Nicholas Toletino (left top); St. Anthony the Great (left center); St. James the Great (left bottom); St. Martin (right top); St. Dominic (right center); and St. Sylvester (right bottom).
Over the Lady Chapel stands a prominent statue of St. Peter; and over the St. Joseph Chapel is one of St. Paul, both carved by Franz Aretz of Pittsburgh.